Karen Lee O'Brien
Passed away on September 5, 2026
Karen Lee O’Brien, nee Markulin, Age 74, of Chicago, passed away peacefully on September 5, 2026, surrounded by her family.
Born on August 16, 1952, in Youngstown, Ohio, Karen was the beloved daughter of Anthony and Martha Markulin. Throughout her life, Karen was known for her dedication and love for her family, her sense of humor, and her ability to make everyone she met feel like a friend.
Karen is survived by her loving husband, Timothy, and her four children, Anthony (Kimberly), Brandee (Jay), Ian, and Tressa. She is also survived by her six grandchildren, Jade (Robert), Anthony Jr. (Andie), Alexa (Will), Atreyu, Ambrosia (Chloe), and Abigail; and her four great-grandchildren, Annabelle, Izabella, Oliver, and Capri.
She also leaves behind her siblings, Mark Markulin and Margo (Markulin) Ewing, along with many extended family members and dear friends. The family wishes to extend special thanks to Aunt Margo, Justin, Loretta, Jeni, Kate, and Megan for their love and support during this time.
A Celebration of Life ceremony is being planned, details will be shared once it is scheduled.
In lieu of flowers, and in accordance with Karen’s wishes, the family asks that donations be made to the Ovarian Research Alliance (ocrahope.org)
Karen will be deeply missed and lovingly remembered by all who knew her. And those that knew her best, know she never said goodbye, ABC-123.
Arrangements Entrusted to Elmwood Chapel, Chicago, Illinois. For funeral info call 773-731-2749.